If you are a person with diabetes, you already know that some drugs cannot be administered other than via injections. Today’s guest works on a solution for these medications to be taken from the inside of the cheek.

You’ll hear:

• how different kinds of drugs are absorbed
• why some drugs, macromolecular drugs, need to be delivered in injections
• how Obaris has overcome this problem
• how drugs such as Ozempic or Mounjaro could be administered painlessly

Dr. David Klein Cerrejon is the CEO of Obaris, a chemist with a PhD in pharmaceutical science specializing in drug delivery. Obaris is a Swiss startup, an ETH spin-off, that develops Octo-Patch, a small, painless patch, resembling an octopus sucker, that you can stick to the inner side of the cheek to administer drugs that are now available only in injections.

Here is more about Obaris:

https://obaris.ch/

If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.

The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.

The small amount of brown fat can make you slim. Too much may kill you.

We just don't know who has it and how much.

But this may change with this test.

You’ll hear about

• brown fat but also white fat and beige fat
• what happens when we have too much brown fat or too little
• a new contrast agent to see brown fat on a CT scan
• that allows targeted therapies for cancer, diabetes, obesity,
• and even longevity

Dr. Andrej Babic is the CEO of Adiposs. A pharmacist with a PhD in medicinal chemistry who developed molecules for the diagnosis of diabetes, obesity, and cancer at the University of Geneva. He holds patents in medical imaging, photodynamic therapy, and nanotechnology.

Adiposs is a Swiss startup that develops ImageBAT, a first-in-class CT contrast agent for brown fat. This can be a game changer in obesity treatments, metabolic diseases, diabetes type 2, and cancer.

https://adiposs.com

If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.

The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.

He dropped his engineering job to run 5 Ironman triathlons in 5 countries

for a cause.

But he did not foresee he would gather so many scientists on the way

that try to find a way to mitigate dementia

You’ll hear

• what does it take to run an Ironman triathlon
• how his family coped with his father’s Alzheimer’s
• how he united several startups and researchers to launch a study on the impact of lifestyle on the epigenetic level – to mitigate dementia

My guest today is Hassan Fadli, a materials engineer with 20 years of experience as a technology lead in the solar energy industry. But we’re not going to speak about photonics. His family history made him turn his life upside down.

He’s founded "5 Ironmans to Beat Alzheimer’s”, a non-profit initiative to run 5 Ironman triathlons in 5 countries in one year. They film a documentary about it, also interviewing dementia specialists, societies, patients, and families in all these countries. After Switzerland and Portugal, there are 3 races ahead in 2024:

in France, Nice – on June the 16 UPDATE: finished and beat his record!
in Sweden, Kalmar – on August the 16
and Spain, Calella-Barcelona – on October the 6th

Follow his Ironman races at:

https://www.5ironmansbeatalzheimer.com/en

If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.

The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.