Join us in this episode, as we delve into a groundbreaking study exploring the dermatopathology of Topical Steroid Withdrawal (TSW). Researchers identified distinct symptoms such as burning, flushing, and thermodysregulation. Their findings discuss NAD+ oxidation and mitochondrial dysfunction due to prolonged topical corticosteroid use. Treatments, including metformin and berberine, showed potential in improving TSW outcomes. Join us as we unpack the clinical implications and future directions of this pioneering research on TSW with Dr. Julie Greenberg.
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Tune in for valuable insights into:
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- The pathophysiology and symptoms of topical steroid withdrawal (TSW)
- The role of mitochondrial dysfunction in TSW
- The impact of prolonged corticosteroid use
- Potential treatments like metformin and berberine
- Clinical implications of the research findings
- Future directions for managing TSW symptoms
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References: https://pubmed.ncbi.nlm.nih.gov/38712043/
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