Showing titles in Contagious Diseases

In the middle of the second century AD, Rome was at its prosperous and powerful apex. The emperor Marcus Aurelius reigned over a vast territory that stretched from Britain to Egypt. The Roman-made peace, or Pax Romana, seemed to be permanent. Then, apparently out of nowhere, a sudden sickness struck the legions and laid waste to cities, including Rome itself. This fast-spreading disease, known now as the Antonine plague, may have been history’s first pandemic. Soon after its arrival, the Empire began its downward trajectory toward decline and fall.

In December 2013, a young boy in a tiny West African village contracted the deadly Ebola virus. The virus spread to his relatives, then to neighboring communities, then across international borders. The world's first urban Ebola outbreak quickly overwhelmed the global health system and threatened to kill millions. In an increasingly interconnected world in which everyone is one or two flights away from New York or London or Beijing, even a localized epidemic can become a pandemic. Ebola's spread sounded global alarms that the next killer outbreak is right around the corner.

For the first time in history, the world shut itself down - by choice - all for fear of a virus, COVID-19, that wasn’t well understood. The government, with the support of most Americans, ordered the closure of tens of thousands of small businesses - many never to return. Almost every school and college in the country sent its students home to finish the school year in front of a computer. Churches cancelled worship services. “Social distancing” went from a non-word to a moral obligation overnight.

In the early hours of Thursday 19 March 2020, the luxury cruise liner Ruby Princess docked at Sydney's Circular Quay, the gateway to Australia. Hours later, 2,700 passengers disembarked. Yet in the middle of a pandemic sweeping the planet, there were no health checks. Over the next few days, the passengers got some bad news. The COVID-19 virus had infected some on the ship, and it spread rapidly. Eventually over 900 passengers and crew would be diagnosed, and 28 would die from the disease.

The problem with pandemics is that people want to forget them. One year, a million Americans are killed by a deadly new virus. The next, everyone is back rooting for the Georgia Bulldogs. The impulse to move on from this particular kind of tragedy is more than a little odd.

Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.

The first patient-to-patient guide for people living with Long COVID—with expert advice and an afterword by the leading research scientist

In mid-January 2020, scientists Ugur Sahin and Özlem Türeci learned of how a new virus that had emerged in Wuhan, China, was spreading. Recognising the threat at once, they dropped everything and committed themselves to developing a vaccine against the disease that would soon be known as COVID-19. No one believed it was possible. But by December, the revolutionary BioNTech-Pfizer mRNA inoculation became the first clinically approved COVID-19 vaccine. Soon it was being injected into the arms of millions, turning the tide on the deadliest pandemic in living memory.

Rachel is a palliative care doctor who looked after some of the most gravely unwell patients on the COVID-19 wards of her hospital. Amid the tensions, fatigue and rising death toll, she witnessed the courage of patients and NHS staff alike in conditions of unprecedented adversity. For all the bleakness and fear, she found that moments that could stop you in your tracks abounded. People who rose to their best, upon facing the worst, as a microbe laid waste to the population. Her new book, Breathtaking, is an unflinching insider's account of medicine in the time of coronavirus.

Reports suggest that over 100m people around the world are living with Long COVID (more than 1.5m in the UK) yet reliable, clear information and guidance remains scarce. This book is the definitive guide to understanding, managing and treating the condition. Written by the world's leading immunologist Professor Danny Altmann and expert patient Gez Medinger, The Long COVID Handbook translates cutting-edge science, patient-led research and practical guidance with clarity.

Epidemiology For Dummies is packed with key concepts, practical applications, and real-life examples in the study of disease transmission and control. It's a must-have for students in all public-health-related fields, and for curious learners, too. This Dummies guide will help you conquer even the trickiest epidemiological concepts. In this introduction to the fascinating, complex science, you'll learn—in terms anyone can understand—all the basic principles of epidemiology, plus how those concepts translate to public health outcomes and policy decisions.

From tuberculosis to bird flu and HIV to coronavirus, these infectious diseases share a common origin story: human interaction with animals. Otherwise known as zoonotic diseases for their passage from animals to humans, these pathogens - both preexisting ones and those newly identified - emerge and reemerge throughout history, sparking epidemics and pandemics that have resulted in millions of deaths around the world. How did these diseases come about? And what - if anything - can we do to stop them and their fatal march into our countries, our homes and our bodies?

An internationally recognized authority on epidemiology, Dr. Rodolfo Saracci, provides a wealth of information on this key field, dispelling some of the myths surrounding the study of epidemiology, and explaining what epidemiology is and how vital it is to the discovery, control, and prevention of disease in world populations. Dr. Saracci provides a general explanation of the principles behind clinical trials, and explains the nature of basic statistics concerning disease.

For Chinese immigrant Wong Chut King, surviving in San Francisco meant a life in the shadows. His passing on March 6, 1900, would have been unremarkable if a city health officer hadn't noticed a swollen black lymph node on his groin - a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong's tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed 10 million lives worldwide.

Lyme disease infects a minimum of 300,000 people per year in the United States and millions more throughout the rest of the world. Symptoms run from mild lethargy to severe arthritis to heart disease to incapacitating mental dysfunction. Although tests have improved over the past decade, they are still not completely reliable, and antibiotics are only partially effective. Up to 35 percent of those infected will not respond to antibiotic treatment or will relapse.

After the unprecedented events of the COVID-19 pandemic, it may be hard to imagine a time not so long ago when deadly diseases were a routine part of life. It is harder still to fathom that the best medical thinking at that time blamed these diseases on noxious miasmas, bodily humors, and divine dyspepsia. This all began to change on a day in April 1676, when a little-known Dutch merchant described bacteria for the first time. Ending Epidemics explains how we came to understand and prevent many of our worst infectious diseases—and double average life expectancy.

By investigating thousands of descriptions of epidemics reaching back before the fifth-century-BCE Plague of Athens to the distrust and violence that erupted with Ebola in 2014, Epidemics challenges a dominant hypothesis in the study of epidemics, that invariably across time and space, epidemics provoked hatred, blaming of the "other", and victimizing bearers of epidemic diseases, particularly when diseases were mysterious, without known cures or preventive measures.

From the masters of storytelling-meets-science, Patient Zero tells the long and fascinating history of disease outbreaks—how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors’ lively style, chapters include gripping medical stories about a particular disease or virus—smallpox, Bubonic plague, polio, HIV—that combine “Patient Zero” narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more.

Paul Farmer has battled AIDS in rural Haiti and deadly strains of drug-resistant tuberculosis in the slums of Peru. A physician-anthropologist with more than fifteen years in the field, Farmer writes from the front lines of the war against these modern plagues and shows why, even more than those of history, they target the poor.

Oxford Case Histories in Infection and Microbiology contains over 45 well structured cases, providing comprehensive coverage of the diagnostic and management dilemmas in clinical microbiology and infectious diseases. Each case comprises of a brief patient history with relevant clinical examination findings, thus insuring the listener is aware of how to confirm a diagnosis rapidly, with reference throughout to laboratory techniques, advice on therapy, epidemiological features, and areas which can be controversial.