In this episode, Margaret unpacks one of the most overlooked pieces of women’s health, and that is detoxification.

She explains why perimenopause creates the “perfect storm” for toxin buildup, hormonal chaos, and inflammation, and how to support your body through this transition with practical, sustainable strategies.

From the liver-gut connection to emotional release, Margaret breaks down why detox isn’t about juice cleanses or quick fixes, but about restoring your body’s ability to process hormones, stress, and toxins efficiently. She shares actionable nutrition, mineral, and lifestyle strategies to improve energy, reduce PMS symptoms, and make your transition into menopause smoother and more empowered.

This episode is a must-listen for women in their late 30s and 40s who are feeling puffy, sluggish, or “stuck” in their health—and ready to finally understand what their body is asking for.

Episode Recap:

• What detox really means—and why it’s not about juice cleanses or saunas {01:20}
• How perimenopause slows detox pathways and raises estrogen load {04:50}
• The “perfect storm” of hormonal, liver, and stress overload during your late 30s–40s {05:40}
• Why liver and gut health determine how your hormones feel {8:53}
• Simple, functional detox support: food, minerals, bile flow, and bowel health {11:18}
• The link between nervous system regulation and hormonal balance {16:20}
• How emotions and stress block your body’s ability to detox {17:26}
• Why supporting detox now creates smoother hormones, better energy, and resilience long-term {20:46}

Links & References:

• Click here to order supplements through Fullscript
• Click here to order peptides with EllieMD, a US based telehealth provider.
• Book a peptide consult zoom call
• Download my GLP 1 Peptide Guide
• Join our 1:1 Coaching Program
• Learn more about working with our team by visiting fueledandfree.com
• Ep. 53 | Castor Oil Packs For Liver Detox, Thyroid, and Skin
• Ep. 67 | Estrogen Dominance In Perimenopause: Why You’re Bloated, Gaining Weight, Moody, & Have Heavy Periods

Connect with me on Instagram @margaretannpowell

**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the guidance of your physician or healthcare provider regarding any medical condition or treatment.

In this episode of the Fueled & Free Podcast, Margaret breaks down one of the most common sources of confusion in the wellness world — the difference between peptides and medications.

She explains what peptides actually are, how they work in the body, and why understanding their role can completely shift how you approach healing, longevity, and fat loss.

Margaret shares how peptides act as natural “messengers” that restore balance and repair, while medications tend to override the body’s systems to control symptoms. She also clarifies why some peptides, like GLP-1s, are regulated as drugs — and how others, such as BPC-157 or NAD+, support regeneration and optimization at the cellular level.

This episode is a must-listen for anyone curious about peptide therapy, confused by what’s “natural” vs. “pharmaceutical,” or ready to make more informed choices about how to support their metabolism, energy, and overall health.

Episode Recap:

• What peptides actually are and how it act as the body’s natural repair messengers {02:24}
• Examples of regenerative peptides like BPC-157, NAD+, and Tesamorelin + Ipamorelin {03:05}
• Why medications are designed to override or block pathways for specific outcomes {05:24}
• The “whisper vs. shout” analogy: peptides restore communication, medications command control {06:53}
• Why GLP-1s are regulated as medications, while other peptides remain wellness compounds {08:11}
• How quality peptides are so important and why these are powerful tools {14:50}
• How to use both strategically — peptides for restoration, medications for stabilization {18:20}
• A mindset shift: asking “Do I need to manage or to heal?” to guide your health decisions {22:05}

Links & References:

• Click here to order peptides with EllieMD, a US based telehealth provider.
• Book a peptide consult zoom call
• Download my GLP 1 Peptide Guide
• Join The Microdose Method GLP Coaching Group
• Join our 1:1 Coaching Program
• Learn more about working with our team by visiting fueledandfree.com
• Ep. 68 | Microdosing GLP-1s / Semaglutides: A Tool for Reducing Inflammation, Weight Loss & Insulin Resistance
  Ep. 75 | My 6 month update on microdosing a GLP 1, how peptides impact cravings, blood sugar, and can be a tool for longevity
  
  

Connect with me on Instagram @margaretannpowell

**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the guidance of your physician or healthcare provider regarding any medical condition or treatment.

In this episode of the Fueled & Free Podcast, Margaret shares her personal experience with microdosing GLP-1 peptides, and observations she’s had having coached clients who are microdosing GLP peptides.

She breaks down how microdosing can minimize side effects, support appetite regulation, and improve metabolic health, while emphasizing that it’s not a one-size-fits-all solution when it comes to fat loss.

Margaret also dives into the nuances of insulin resistance, hormone balance, and gut health — explaining why each person’s response to GLP-1s is unique, i.e. why some need a higher dose to get their body to respond.

This episode challenges the misconception that needing a higher dose means failure, and instead reframes it as part of a personalized journey toward better health.

Episode Recap:

• What microdosing really means and why it’s a smart, gentle starting point {01:42}
• Why microdosing can fall short for fat loss if deeper metabolic issues exist {03:47}
• Five reasons your body may not respond on a low dose (insulin resistance, receptor sensitivity, thyroid, undereating, gut health) {09:18}
• How to know when it’s time to move from microdosing to a therapeutic dose {17:09}
• Why needing a higher dose is not failure—it’s feedback from your body {24:44}
• The importance of flexibility over rigidity in your dosing journey {31:21}
• Why the microdosing phase still matters, even if you eventually titrate {32:00}

Links & References:

• Click here to order peptides with EllieMD, a US based telehealth provider.
• Book a peptide consult zoom call
• Download my GLP 1 Peptide Guide
• Join The Microdose Method GLP Coaching Group
• Join our 1:1 Coaching Program
• Learn more about working with our team by visiting fueledandfree.com
• Ep. 79 | How expectations can sabotage healing, lessons on letting go of timelines & surrendering to your health journey
• Ep. 75 | My 6 month update on microdosing a GLP 1, how peptides impact cravings, blood sugar, and can be a tool for longevity

Connect with me on Instagram @margaretannpowell

**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the guidance of your physician or healthcare provider regarding any medical condition or treatment.

In this episode of the Fueled & Free Podcast, Margaret has an honest conversation about one of the most common questions she hears: “How long is this going to take?” Whether it’s balancing hormones, healing the gut, improving energy, or reaching weight loss goals, many women expect a clear timeline. But the body doesn’t work that way.

Instead, Margaret reframes the process of health and healing — comparing it to learning a new skill that takes time, practice, and patience. She emphasizes why expectations can become one of the biggest obstacles to progress, and how showing up consistently with the right support makes the difference.

This conversation sheds light on why healing is not a quick fix, but a personal journey that requires patience, consistency, and a willingness to embrace the process.

Episode Recap:

• Why “How long will this take?” is the wrong question to ask {00:53}
• How expectations can sabotage real healing {01:21}
• Why health journeys are like learning a new skill — and can’t be rushed {02:42}
• The truth about timelines for gut healing, hormone balance, and metabolism {07:28}
• The cultural obsession with “perfect health” and why it’s unrealistic {09:06}
• How functional testing helps remove barriers slowing your progress {13:25}
• A better question to ask yourself instead of “How long?” {13:40}
• Why creating space for healing, and showing up matter more {16:07}

Links & References:

• Click here to order peptides with EllieMD, a US based telehealth provider.
• Book a peptide consult zoom call
• Download my GLP 1 Peptide Guide
• Join The Microdose Method GLP Coaching Group
• Join our 1:1 Coaching Program
• Learn more about working with our team by visiting fueledandfree.com

Connect with me on Instagram @margaretannpowell

**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the guidance of your physician or healthcare provider regarding any medical condition or treatment.

In this episode of the Fueled & Free Podcast, Margaret explores the reality of PMS and PMDD, especially for women in their 30s and 40s. She challenges the conventional approach of prescribing birth control as a “fix,” explaining why it fails to address the root causes of hormonal imbalance.

Instead, she highlights the role of bioidentical progesterone in easing symptoms, supporting perimenopause, and protecting long-term health.

This conversation sheds light on why women need real hormone support — not suppression — and how understanding progesterone’s benefits can transform mental health, sleep, and overall well-being.

Episode Recap:

• Why birth control is the default prescription for PMS, PMDD, and perimenopause symptoms {01:53}
• How medical training and pharma influence keep doctors from addressing root causes {04:59}
• Why suppressing ovulation in perimenopause makes symptoms worse, not better {06:08}
• The critical difference between synthetic progestins and natural progesterone {07:32}
• How bioidentical progesterone supports mood, sleep, metabolism, and long-term health {09:26}
• The outdated fears around hormone therapy—and why they don’t apply to progesterone {11:10}
• Best practices for progesterone use—and how to know if it’s working for you {13:26}
• Questions to ask your provider so you can advocate for better hormone care {24:04}

Links & References:

• Access hormone replacement therapy from Raena Health, a US based telehealth provider.
• Taking Charge Of Your Fertility Book on Amazon.
• Click here to order peptides with EllieMD, a US based telehealth provider.
• Book a peptide consult zoom call
• Download my GLP 1 Peptide Guide
• Join The Microdose Method GLP Coaching Group
• Learn more about working with our team by visiting fueledandfree.com
• Ep. 67 | Estrogen Dominance In Perimenopause: Why You’re Bloated, Gaining Weight, Moody, & Have Heavy Periods

Connect with me on Instagram @margaretannpowell

**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the guidance of your physician or healthcare provider regarding any medical condition or treatment.

In today’s episode I’m sharing real talk on the cost of GLP-1 peptides like semaglutide and tirzepatide, what insurance does (and doesn’t) cover, and what it actually takes to maintain results long term.

These medications can be powerful tools for weight loss and metabolic health, but they’re not quick fixes. That’s why it’s so important to understand not just the financial side, but also the lifestyle shifts, maintenance strategies, and functional testing that truly support lasting results.

I’ll walk you through what you can expect if you’re paying cash, what insurance may cover depending on BMI or health conditions, why weight regain is such a common challenge, and how strength training + holistic health strategies fit into the picture.

You deserve clarity, and you deserve support in making these decisions with eyes wide open.

Episode Recap:

• How much GLP-1s really cost — and why so many women ask this question {00:43}
• When insurance typically covers GLP-1s and when it almost never does {01:20}
• What cash pay looks like at pharmacies, medspas, and telehealth platforms {05:42}
• How long you might actually need to be on a GLP-1, and why weight regain is common {09:19}
• What maintenance really looks like: strength training, protein, gut health, and hormones {13:39}
• Why functional testing still matters, even if GLP-1s are working {20:25}
• The hidden cost of not addressing metabolic issues early {25:39}
• Why GLP-1s are more than weight loss drugs — they’re metabolic therapies {26:41}

Links & References:

• Click here to order peptides with EllieMD, a US based telehealth provider.
• Book a peptide consult zoom call
• Download my GLP 1 Peptide Guide
• Join The Microdose Method GLP Coaching Group
• Learn more about working with our team by visiting fueledandfree.com
• Ep. 68 | Microdosing GLP-1s / Semaglutides: A Tool for Reducing Inflammation, Weight Loss & Insulin Resistance
• Ep. 75 | My 6 month update on microdosing a GLP 1, how peptides impact cravings, blood sugar, and can be a tool for longevity

Connect with me on Instagram @margaretannpowell

**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the guidance of your physician or healthcare provider regarding any medical condition or treatment.

Today’s episode is all about something I know so many of you have struggled with: that constant chatter in your head around food. The “should I eat this?” … “why can’t I stop?” … “just one more bite” loop that feels like it never shuts off. This “food noise” can feel exhausting, overwhelming, and even isolating.

In this episode, I’m diving into how GLP-1 medications can quiet that food noise, shift the urge to binge, and create more freedom in your relationship with food. We’ll talk about the connection between dopamine, ADHD, and binge eating, and how microdosing GLP-1s can bring calm where there used to be chaos.

I’ll also share the flip side of this, because while reduced appetite and food noise can be a relief, some people find that eating loses its pleasure. That’s why it’s so important to reframe our relationship with food from an emotional tug-of-war into something more neutral, where food supports life instead of consuming your thoughts non stop.

Episode Recap:

• How GLP-1s can change your relationship with food {00:37}
• What “food noise” is and why it leaves so many women feeling exhausted and hopeless {01:36}
• The link between ADHD, dopamine-seeking, and impulsive eating or drinking {03:37}
• How GLP-1s quiet brain chatter, blunt binge urges, and soften dopamine hits {06:28}
• The freedom that comes with food taking up less mental space {08:49}
• The flip side: when eating feels less pleasurable and more neutral {09:28}
• Reframing neutrality around food as empowerment rather than loss {14:51}
• Why GLP-1s are about more than appetite—they reshape mindset, habits, and pleasure {16:11}

Links & References:

• Click here to order peptides with EllieMD, a US based telehealth provider.
• Book a peptide consult zoom call
• Download my GLP 1 Peptide Guide
• Join The Microdose Method GLP Coaching Group
• Ep. 68 | Microdosing GLP-1s / Semaglutides: A Tool for Reducing Inflammation, Weight Loss & Insulin Resistance
• Ep. 75 | My 6 month update on microdosing a GLP 1, how peptides impact cravings, blood sugar, and can be a tool for longevity

Connect with me on Instagram @margaretannpowell
Learn more about working with our team by visiting fueledandfree.com

**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the guidance of your physician or healthcare provider regarding any medical condition or treatment.

Today’s episode is a special one because we’re celebrating 75 episodes of the Fueled & Free Podcast! 🎉 In today's episode, I’m sharing my six-month update on microdosing a GLP-1 peptide, Tirzepatide.

This hasn’t been about chasing shortcuts or finding an “easy way out,” but rather giving my body the support it needed to finally respond again. Over the past six months, I’ve seen not just physical changes in body composition and cravings, but also shifts in my mental health and the way I view wellness as a whole.

I know this is not for everyone, and I’m not here to tell you what to do, but I am here to share openly about what has been a game changer for me and for so many women I’ve worked with. You are NOT broken. And you don’t have to white-knuckle your way through your health journey to create real change. If you’ve been curious about peptides, weight loss, or even the stigma around weight management, this episode will encourage you to explore your options without shame.

Episode Recap:

• My six-month update on microdosing GLP-1 {1:08}
• Physical changes, body composition, and reduced cravings {06:30}
• Exploring peptides and how they benefit in many ways {10:59}
• Cultural shifts in weight loss & public conversations (Serena Williams, etc.) {16:34}
• Why emotional health is just as important as physical health {22:19}
• The stigma around weight loss + how I worked through it {23:04}
• Long-term use of GLP-1 and who it may help {31:06}
• Why you deserve support and education in your journey {38:12}
• Letting go of shame and embracing your health choices {44:23}

Links & References:

• Click here to order peptides with EllieMD, a US based telehealth provider.
• Book a peptide consult zoom call
• Download my GLP 1 Peptide Guide
• Join The Microdose Method GLP Coaching Group
• Ep. 68 | Microdosing GLP-1s / Semaglutides: A Tool for Reducing Inflammation, Weight Loss & Insulin Resistance
• Ep. 74 | Feeling puffy, inflamed and stuck with your weight? Sharing my honest experience in microdosing a GLP 1.

Connect with me on Instagram @margaretannpowell
Learn more about working with our team by visiting fueledandfree.com

**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the guidance of your physician or healthcare provider regarding any medical condition or treatment.