This episode features Dr Jason Fung, a Nephrologist (Kidney Doctor) who has spent over 25 years researching the best way to lose weight and prevent disease. In this episode, Dr Fung discusses the causes of obesity and how hormones play a vital role in fat storage and weight gain. Dr Fung discusses the difference between the hormonal theory and the calories theory, pertaining to the best way to lose adipose fat and regain metabolic health. Access the full show notes, including referenced articles, books, and additional resources: https://www.5minutebody.com/lab/the-root-cause-of-obesity-chronic-disease-and-how-fasting-prevents-it Dr Fung discusses the key hormone of insulin, how elevated levels of insulin in the body lead to chronic inflammation, and the physiology of how this happens. Dr Fung explains how certain foods we eat elevate insulin and cause us to store fat in the fat cells. And while what we eat matters, when we eat is also important to release adipose tissue (body fat). Dr Fung discusses the role of intermittent fasting, extended fasting, and autophagy to reduce inflammation and why the consumption of too much protein can inhibit autophagy and mitophagy. Dr. Fung also discusses the role of common weight loss medications like Ozempic and their effect on weight loss and insulin resistance. This episode is important for anyone who is overweight, those who have tried every diet or count calories and failed, and who seek to know the science behind how to lose weight and keep it off. You will learn the science of lipolysis (how the body burns fat) and effective dietary and lifestyle protocols to improve metabolic health and fix obesity.