A woman is found murdered in a Michigan park, bound with police-grade, plastic handcuffs. Investigator’s prime suspect is found with identical cuffs in his possession, but without any additional clues detectives must get creative to link his cuffs to their evidence.

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The 1964 murder of 9-year-old Marise Chiverella leaves the devout town of Hazelton, PA, in fear. An intense manhunt yields numerous suspects but no killer. Five decades pass before a student moonlighting as a genetic genealogist reignites the case.

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April is brutally assaulted then set on fire by an acquaintance after taking them and her ex-boyfriend for a ride. Mark is forced to amputate part of his leg after it is caught in a drive shaft of an oil well. An act of kindness backfires on Jesse when he is attacked with a hammer and run over by the hitchhikers he reluctantly gave a ride

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A district attorney uses a clever technique - a "John Doe indictment" - to give law enforcement officials the time they need to track down the a serial rapist from Rochester, N. Y.

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When 19-year-old Chris Green is found beaten to death in a snowy Bangor, Michigan ditch in 2002, his family fear their son's murder will never be solved. Years pass before shocking revelations from an informant emerge and blow the case wide open.

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A hitchhiker is murdered, and a mysterious stack of business cards leads police on a 38-year hunt for her killer.

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The quiet town of Redding, California is rocked by the disappearance of Frank McAlister - a teen with a recent cash windfall who leaves only a blood-stained car behind. Twenty-five years will pass before someone makes a stunning on-air confession.

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