Hyponatraemia, the most common electrolyte disturbance in clinical medicine, is often subtle but can be serious.

In this episode, we trace the surprising history of fluid replacement back to the 1832 cholera riots in Liverpool, where experimental saline saved lives amidst chaos and mistrust.

We then bring the conversation into modern practice, exploring diagnostic steps, common causes, and when GPs should refer patients to hospital.

This is the story of Hyponatraemia.

Our special guest is:

Dr Michael Page, Chemical Pathologist and CEO of Clinipath.

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In 1958, Dr Denis Burkitt was working in Uganda when he saw multiple children with large and aggressive jaw tumours. He had never seen anything like this before and he investigated further. Over the next few years, he discovered that these tumours had a geographical distribution across equatorial Africa and also was related to rainfall.

This led to the discovery of an aggressive form of lymphoma that we now know as Burkitt lymphoma as well as the Epstein-Barr virus (EBV). It is a remarkable story of intellectual curiosity, scientific discovery, and commitment.

Éanna Mac Cana was diagnosed with Burkitt lymphoma in 2017. This diagnosis led him to the story of Dr Denis Burkitt and how we first learned about this disease. He has created a documentary using never-before-seen archival footage of Dr Denis Burkitt and his discovery, and included his own journey with this disease.

This is the story of Burkitt lymphoma.

Our special guests include:

Éanna Mac Cana who is a documentary filmmaker from Belfast in Ireland.

Professor Jonathan Bond from the University College Dublin and works in paediatric molecular haemato-oncology.

This Medical Life podcast is available on all podcasting services and Spotify.

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Osteoporosis is a disease that takes years and even decades to develop. Up to 40% of post-menopausal women are affected who have a lifetime risk of fracture of ~40%. Men aged 60 have a 25% lifetime risk of an osteoporotic fracture. Evidence also shows that patients health significantly deteriorates following a significant fracture.

The best treatment for osteoporosis is prevention. We discuss this disease, lifestyle, diagnosis, and management with a panel of experts at COMBATT: Comprehensive Osteoporosis Management workshop, at the Adelaide Convention Centre in February 2025.

This is the story of osteoporosis.

Our special guests:

Our special guests are:

Dr Alecia Macrow: General Practitioner

Dr Nick Kasmeredis: Endocrinologist

Dr Steve Soukoulis: Periodontist

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Recent genetics studies have shown that ancient Humans and Neanderthals coexisted around 50,000 years ago for approximately 7,000 years. There is evidence of these different human species mixing and having offspring. Around 2-4% of modern humans can be traced back to Neanderthals.

This is the story of Humans and Neanderthals.

Our special guests:

Our special guest is Associate Professor Bastien Llamas who is affiliated with the Australian Centre for Ancient DNA.

This Medical Life podcast is available on all podcasting services and Spotify.

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And we’re back for 2025. We thought we’d ease into this season with some medical stories. From the Manhattan project and the demon core to the inspirational stories of Dr Elizabeth Blackwell, Dr Elizabeth Garrett Anderson, and Dr Emma Constance Stone. We are reaching back into the medical archives.

Our special guests:

Dr Travis Brown, himself!

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Patients with colorectal cancer often have their diagnosis, treatment, and care discussed at a regular multidisciplinary team meeting. This includes: gastroenterologists, surgeons, oncology, radiation oncology, pathologists, home care nurses, oncology nurses, genetic councillors, care coordinators plus others.

This is the third episode of a three part series on colorectal cancer.

This episode focuses on management.

Many thanks to Dr Tristan Rutland who helped organise this series.

This is the story of colorectal cancer (part 3).

Our special guests:

Dr Stephanie Lim: medical oncologist who works at GenesisCare and Macarthur Cancer Therapy Centre

Dr Meredith Johnston: radiation oncologist who works at Liverpool hospital

Dr Emilia Ip: medical oncologist and cancer geneticist at Liverpool hospital

This Medical Life podcast is available on all podcasting services and Spotify.

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The lifetime risk for colorectal cancer is 1 in 23 men and 1 in 25 women. Detecting and diagnosing cancer is a critical step in managing a patient’s health as well as the multidisciplinary team where their care is discussed.

This is the second episode of a three part series on colorectal cancer.

This episode focuses on diagnosis.

Many thanks to Dr Tristan Rutland who helped organise this series.

This is the story of colorectal cancer (part 2).

Our special guests:

Dr Milan Bassan: gastroenterologist and Director of Endoscopy at Liverpool Hospital and returning guest

Dr Scott Mackenzie: surgeon and senior lecturer at the Liverpool Hospital and returning guest

Dr Tristan Rutland: lecturer, award winning anatomical pathologist for teaching and regular guest

This Medical Life podcast is available on all podcasting services and Spotify.

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Colorectal cancer accounts for ~10% of all new cancer diagnoses. Fortunately, over the last three decades, the 5 year patient survival has increased from 56% to 71%. As with most cancers, the key to good outcomes is early detection. This is the first episode of a three part series on colorectal cancer. This episode focuses on screening.

Many thanks to Dr Tristan Rutland who helped organise this series.

This is the story of colorectal cancer (part 1).

Our special guests are:

Professor Ken Sikaris: chemical pathologists, Director of Chemical Pathology at Dorevitch Pathology and regular guest

Dr Milan Bassan: gastroenterologist and Director of Endoscopy at Liverpool Hospital and returning guest

Dr Tristan Rutland: lecturer, award winning anatomical pathologist for teaching and regular guest

This Medical Life podcast is available on all podcasting services and Spotify.

See omnystudio.com/listener for privacy information.