In this episode of Aggressive Salad, host Abby Langer is joined by brothers Dr. Carl and Dr. Spencer Nadolski. The Nadolski brothers are medical professionals specializing in lipidology, obesity medicine, internal medicine, endocrinology, and family medicine. They discuss their careers and contributions to obesity management, including Spencer's role as the medical director for Weight Watchers and Carl's creation of a new endocrinology and obesity department in Michigan. The conversation delves deep into the use of GLP-1 agonists like Ozempic for weight loss, detailing their mechanisms, safety, and effectiveness compared to traditional approaches like bariatric surgery. They also touch on the psychological and physiological aspects of obesity, such as genetic factors and the concept of 'food noise.' The episode emphasizes the importance of comprehensive, personalized treatment plans and the potential future of obesity medication. Additionally, the talk addresses common misconceptions about cortisol and stress, debunking myths often perpetuated on social media.

01:51 Discussing Weight Loss and GLP-1 Agonists

03:11 Mechanisms and Benefits of GLP-1 Agonists

08:44 Genetics and Obesity

15:26 Comparing Medications and Bariatric Surgery

20:12 Safety Concerns and Side Effects

29:54 The Dangers of Unstudied Weight Loss Methods

31:44 Obesity as a Disease: A Controversial Perspective

32:38 Understanding the Definition of Obesity

33:20 Patient Communication and Stigma in Obesity

34:05 The Role of Lifestyle in Managing Obesity

34:43 The Herpes Analogy: Choice vs. Disease

35:45 Obesity-Related Complications and Misconceptions

37:54 The Myth of the Cortisol Diet

38:37 Cortisol and Its Impact on Health

41:44 The Role of Cortisol in Stress and Weight Gain

44:44 The Misuse of Hormone Tests and CGMs

50:40 The Benefits and Misconceptions of CGMs

52:18 Final Thoughts and Podcast Wrap-Up

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LINKS

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GUEST:

Follow Dr. Spencer Nadolsky here: https://www.instagram.com/drnadolsky/

Follow Dr. Karl Nadolsky here: https://www.instagram.com/drkarlnadolsky/

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