Physical Biology

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

We may believe that we are the masters of our fates, but in reality, we are at the mercy of hundreds of trillions of single-celled organisms that exert control over every aspect of how our minds and bodies function. These are the diverse species of microbes that work together synergistically to communicate with each other and with every system in our bodies. You are your microbiome’s home, and it wants to take care of you, but first you have to protect it. In Gut Check, Dr. Steven Gundry reveals the emerging science proving that Hippocrates was right—all disease begins in the gut.

A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.

In Cancer and the New Biology of Water, Thomas Cowan argues that this failure was inevitable because the oncogene theory is incorrect or at least incomplete and based on a flawed concept of biology in which DNA controls our cellular function and therefore our health. Instead, Dr. Cowan tells us the somatic mutations seen in cancer cells are the result of a cellular deterioration that has little to do with oncogenes, DNA, or even the nucleus.

In 2017, author Shanna Swan and her team of researchers completed a major study. They found that over the past four decades, sperm levels among men in Western countries have dropped by more than 50 percent. They came to this conclusion after examining 185 studies involving close to 45,000 healthy men. The result sent shockwaves around the globe - but the story didn’t end there.

Until recently, microglia were thought to be merely the brain’s housekeepers, helpfully removing damaged cells. But a recent groundbreaking discovery revealed them to be capable of terrifying Jekyll and Hyde behavior. When triggered - and anything that stirs up the immune system in the body can activate microglia - they can morph into destroyers, impacting a wide range of issues from memory problems and anxiety to depression and Alzheimer’s. Under the right circumstances, however, microglia can be coaxed back into being angelic healers.

We have lost the war on cancer. We spend $150 billion each year treating it, yet - a few innovations notwithstanding - a patient with cancer is as likely to die of it as one was 50 years ago. Most new drugs add mere months to one's life at agonizing physical and financial cost. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must.

Perched on the exterior of our delicate and intricate bodies, the skin is our largest and fastest growing organ. We see it, touch it and live in it every day. It's a habitat for a mesmerisingly complex world of micro-organisms, its physical functions are vital to our health and indeed our survival, and it's crucial to our sense of identity. Yet how much do we really know about it? Through the lenses of science, sociology and history, Dr Monty Lyman leads us on a journey through the comedy, tragedy and exquisite humanity of our most underrated and overlooked organ.

The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Professor Daniel Davis describes the scientific quest to understand how it works - and how it is affected by stress, sleep, age and our state of mind - and explains how this knowledge is now unlocking a revolutionary new approach to medicine and well-being.

The form and function of a sprinting cheetah are quite unlike those of a rooted tree. A human being is very different from a bacterium or a zebra. The living world is a realm of dazzling variety, yet a shared set of physical principles shapes the forms and behaviors of every creature in it. So Simple a Beginning shows how the emerging new science of biophysics is transforming our understanding of life on Earth and enabling potentially lifesaving but controversial technologies such as gene editing, artificial organ growth, and ecosystem engineering.

Biogeography is the study of geographic variation in all characteristics of life - ranging from genetic, morphological, and behavioral variation among regional populations of a species, to geographic trends in diversity of entire communities across our planet's surface. From the ancient hunters and gatherers to the earliest naturalists, Charles Darwin, Alfred Russel Wallace, and scientists today, the search for patterns in life has provided insights that proved invaluable for understanding the natural world.

Over the past 200 years, human life expectancy has approximately doubled. Yet we face soaring worldwide rates of obesity, diabetes, high blood pressure, mental illness, heart disease, and stroke. In his fascinating new book, Dr. Lee Goldman presents a radical explanation: The key protective traits that once ensured our species' survival are now the leading global causes of illness and death.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

An award-winning scientist offers a groundbreaking new understanding of the mind-body connection and its profound impact on everything from advertising to romance. The human body is not just a passive device carrying out messages sent by the brain but rather an integral part of how we think and make decisions.

Gut: An Owner's Guide is an informative, practical, and engaging introduction to this hidden-away part of the body. We tend to only pay attention to our gut when it tries to tell us something - when it feels uncomfortable or something goes wrong. This myth-busting audiobook focuses on all aspects of gut health, so you can steer clear of Dr Google and find out what will really make your gut happier and healthier.

Millions of Americans suffer from hearing loss. Faced with the cost and stigma of hearing aids, the natural human tendency is to do nothing and hope for the best, usually while pretending that nothing is wrong. In Volume Control, David Owen argues this inaction comes with a huge social cost. He demystifies the science of hearing while encouraging listeners to get the treatment they need for hearing loss and protect the hearing they still have.

In spring of 1918, World War I was underway, and troops at Fort Riley, Kansas, found themselves felled by influenza. By the summer of 1918, the second wave struck as a highly contagious and lethal epidemic and within weeks exploded into a pandemic, an illness that travels rapidly from one continent to another. It would impact the course of the war, and kill many millions more soldiers than warfare itself.

Flush is both an urgent exploration of the world’s single most squandered natural resource, and a cri de coeur (or cri de colon?) for the vast, hidden value in our “waste.” Award-winning journalist and microbiologist Bryn Nelson, PhD, leads listeners through the colon and beyond with infectious enthusiasm, helping to usher in a necessary mental shift that could restore our balance with the rest of the planet and save us from ourselves.

The human body is like an exceedingly well-fortified castle, defended by billions of soldiers - some live for less than a day, others remember battles for decades, but all are essential in protecting us from disease. This hidden army is our immune system, and without it we could not survive the eternal war between us and our microscopic enemies. Immune explores the incredible arsenal that lives within us - how it knows what to attack and what to defend and how it kills everything from the common cold to the plague bacterium.

As dramatic as The Double Helix and as absorbing as The Soul of a New Machine, Natural Obsessions explores the advanced reaches of molecular biology, the nature of the human cell, and the genes that control cancer. It unforgettably portrays some of the best young scientists in the world, the rewards and discouragements of scientific research, and the very process of scientific inquiry.