Genetic Disease

Nessa Carey’s The Epigenetics Revolution looks at how modern biology is rewriting our understanding of genetics, disease and inheritance....

In Beat the Heart Attack Gene, world-renowned cardiovascular specialists Bradley Bale, MD, and Amy Doneen, ARNP, present a new model for understanding and preventing heart disease. They explain the three different genetic types of cholesterol profiles and tailor treatments for each type, using their cutting-edge Bale/Doneen Method, a simple, comprehensive prevention plan that detects cardiovascular disease (CVD) at early stages.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.

A Sick Life chronicles Tionne's journey from a childhood spent in and out of the hospital, told she wouldn't live to see 30 or have children, to becoming the superstar musician who is still living out her life's dream of performing. For the first time, Tionne will tell her full life story - the diagnosis, the tumultuous rise to fame, the life in the spotlight, and the hard-fought advocacy work.

In this book, biotechnology entrepreneur and CEO of The DNA Company Kashif Khan offers an action plan to help you live your best life. It starts by understanding your genetic makeup.

Perched on the exterior of our delicate and intricate bodies, the skin is our largest and fastest growing organ. We see it, touch it and live in it every day. It's a habitat for a mesmerisingly complex world of micro-organisms, its physical functions are vital to our health and indeed our survival, and it's crucial to our sense of identity. Yet how much do we really know about it? Through the lenses of science, sociology and history, Dr Monty Lyman leads us on a journey through the comedy, tragedy and exquisite humanity of our most underrated and overlooked organ.

Contrary to conventional wisdom, chronic disease is not genetically predetermined but results from a mismatch between our genes and environment and lifestyle. What we call a "disease" is the outcome of an imbalance in one or more of the seven core physiological processes. Leveraging a lifetime on the cutting edge of research and practice, Dr. Jeffrey S. Bland lays out a road map for good health by helping us understand these processes and the root causes of chronic illness.

A leading brain scientist's look at the neurobiology of pleasure-and how pleasures can become addictions. Whether eating, taking drugs, engaging in sex, or doing good deeds, the pursuit of pleasure is a central drive of the human animal. In The Compass of Pleasure Johns Hopkins neuroscientist David J. Linden explains how pleasure affects us at the most fundamental level: in our brain.

For patients with chronic pain and those who love them, an exploration of the causes of and treatments available for those with hypermobility.

Did you know that about 10,000 years ago humans went through a radical change in lifestyle in what is now called the Agricultural Revolution? While this event propelled humans out of the stone age and into civilization it also ultimately catapulted us into our current way of life and into the chronic disease epidemic we have today. Western medicine sees our epidemic of disease as a problem that needs to be suppressed, but our chronic disease epidemic is really a symptom.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

For the past six years, Whitney Dafoe has been confined to a bedroom in the back of his parents' home, unable to walk, eat or speak. His diagnosis? The mysterious disease myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) which affects 20 million people around the world who largely suffer in silence because the condition is little known and much misunderstood. Waiting for Superman follows Whitney's father, groundbreaking geneticist Ron, as he uncovers new possibilities for treatments and potentially a cure.

Do you live with a chronic, debilitating, yet invisible condition? You may feel isolated, out of step, judged, lonely, or misunderstood - and that's on top of dealing with your actual illness. Take heart. You are not alone, although sometimes it can feel that way. Written by a blogger who suffers from an invisible chronic illness, Surviving and Thriving with an Invisible Chronic Illness offers peer-to-peer support to help you stay sane, be your own advocate, and get back to living your life. This compelling guide is written for anyone suffering with an illness no one can see.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones... to which this book says: Pure nonsense.

p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

Eine faszinierende Vorstellung: Wie wäre es, wenn sich die biologische Uhr, die in jedem von uns tickt, anhalten ließe – oder sogar ein Stück zurückdrehen? Und das nicht bloß gefühlt, sondern messbar? Dieses Versprechen ist seit Kurzem Realität. Der junge Forschungszweig der Epigenetik hat den Deckel von der Altersuhr gehoben – und in aktuellen Studien nun sogar den Sprung in die praktische Anwendung geschafft. Genau darum geht es in diesem Hörbuch: Was kann ich ganz konkret tun, um meine Altersuhr zurückzudrehen? Um wie viele Monate oder gar Jahre lässt sich der Zeiger zurückstellen?