• What have organoids ever done for me? Translating science in a dish to patient outcomes.

  • Nov 21 2024
  • Length: 52 mins
  • Podcast

What have organoids ever done for me? Translating science in a dish to patient outcomes.

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  • Summary

  • What have organoids ever done for me?
    Translating science in a dish to patient outcomes.

    Special guests:
    Surgeon-scientist Prof. Dr. med. Bernhard Kiss, Inselspital and
    Prof. Roland Seiler-Blarer, Head of Urology at the Hospital Center in Biel.
    Bios here.

    Key moments:

    00:01:13
    Marianna has a new paper accepted in Oncogene that is on organoids.
    You can enjoy also how we can measure weight and density on organoids.
    Steven also has new paper on sample clean-up for drug and drug
    metabolism studies for organoids.

    00:02:23

    Introducing our guests and why they are working with organoids: Prof. Dr. med. Bernhard Kiss, Oncology surgeon-scientist. University Hospital, Bern. Prof. Roland Seiler-Blarer, Head of Urology at the Hospital Center in Biel.

    00:04:33
    What do we we mean by dish science helping patients?
    And do organoid responses to drugs really relate to human responses?
    Are there any ways to benchmark the work?

    00:09:23
    How do you also run a clinical trial? How do you group patients? Do you have a control group?

    00:11:33
    What are the general opinions on organoid co trials? Can they really be used? Are they being used and how does it work? What is required? What re the limiting factors? How important are collaborations and communication?
    Challenges of scepticism faced?

    00:17:53
    Validation and the quality of organoid science adopted. Differences of adopting long and short term culture organoid durations and organoid lines.

    00:24:14
    Reporting of all information accurately from different oncology cases. Cookbook questions?

    00:27:17
    We say goodbye to Roland and talk on ethics and clinical trials relating to organoids. What are the ethical concerns? Who owns the IP of of the organoid of the patient?

    00:33:00
    Billion dollar question Where would spend the money? Technologies, training, resources?

    00:40:55
    Finding information that helps.

    00:43:45
    Research we are excited about?

    00:48:56
    What’s happening until the end of the year?

    00:51:39
    That’s it bye everyone!

    Visit the HOME of the Podcast here: WORC.Community

    Visit the HOME of the Podcast here: WORC.Community
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