Episodes

  • Unlocking Bryson's Brain - Trailer

    Unlocking Bryson's Brain - Trailer
    Feb 24 2020
    Bryson is a beautiful, happy boy. But a mysterious illness means he can’t walk, talk, or feed himself. Scientists working at the cutting edge of genetics believe they know what’s causing Bryson’s disease — and think it could be reversed. Motivated by the hope for a cure, Bryson’s parents search for the miracle key that could unlock Bryson’s brain. Hosted by Keith McArthur, coming April 2020.
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    4 mins
  • Unlocking Bryson's Brain, Episode 1: The Mystery Disease

    Unlocking Bryson's Brain, Episode 1: The Mystery Disease
    Apr 13 2020
    Bryson seems like a perfectly healthy baby. But soon doctors confirm his parents’ worst fears: something is wrong with Bryson’s brain. Despite dozens of tests over nearly a decade, doctors come up empty in their efforts to find a diagnosis.
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    53 mins
  • Unlocking Bryson's Brain, Episode 2: Getting a Diagnosis

    Unlocking Bryson's Brain, Episode 2: Getting a Diagnosis
    Apr 13 2020
    From violent seizure-like episodes to insensitive comments from strangers, Bryson has a hard life. But after years of searching, doctors finally provide a diagnosis. The news changes everything for Bryson’s parents and provides a possible path to new treatments — or even a cure.
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    45 mins
  • Unlocking Bryson's Brain, Episode 3: The CRISPR Revolution

    Unlocking Bryson's Brain, Episode 3: The CRISPR Revolution
    Apr 20 2020
    Bryson’s parents explore CRISPR, a new technology with the potential to cure dozens of diseases once thought incurable. But gene editing comes with risks — not just for individual patients, but for the human race.
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    34 mins
  • Unlocking Bryson's Brain, Episode 4: A New Hope

    Unlocking Bryson's Brain, Episode 4: A New Hope
    Apr 27 2020
    Bryson’s family travels to meet other GRIN1 patients, including Bryson’s GRIN-twin Olivia. And research on mice offers new hope for finding a cure. But a new illness means that the family now needs two medical miracles.
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    53 mins
  • Unlocking Bryson's Brain, Episode 5: Making a Mouse

    Unlocking Bryson's Brain, Episode 5: Making a Mouse
    May 4 2020
    Scientists in Toronto get to work building a mouse with Bryson’s precise genetic variant. Plus, the family travels to Atlanta to provide blood samples for a researcher to create DNA-based “mini-brains” in his lab. Could this cutting edge science provide clues to unlocking Bryson’s brain?
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    43 mins
  • Unlocking Bryson's Brain, Episode 6: The Ethics of Cure

    Unlocking Bryson's Brain, Episode 6: The Ethics of Cure
    May 11 2020
    Finding a cure for Bryson no longer seems impossible. And that raises new questions about the ethics of this journey. Bryson’s family seeks out new perspectives and learns why “cure” is a loaded term in the disability rights community.
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    50 mins
  • Unlocking Bryson's Brain, Episode 7: Pilgrimage to Boston

    Unlocking Bryson's Brain, Episode 7: Pilgrimage to Boston
    May 18 2020
    Bryson’s parents travel to Boston/Cambridge, the global capital for rare disease research. Their goal: to ask private biotech companies to help in their search for a cure. Scientists provide new clues, but also raise difficult questions.
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    41 mins