Meet Kasia Harris - an expert in clinical trial feasibility and planning with experience in both CRO and Pharma. bringing valuable insights into the complexities of global healthcare systems. In this episode, Kasia and Maya delve into the critical role of understanding local standard of care in clinical trial success. They explore feasibility assessments, protocol, country, and site-specific considerations. Kasia highlights how standard of care impacts patient enrollment, country and site selection, and overall trial efficiency. This episode is a must listen for anyone involved in planning or conducting international clinical trials.

Follow Maya Zlatanova: https://www.linkedin.com/in/mayazlatanova/

Follow Kasia Harris: https://www.linkedin.com/in/kasia-harris-md-16316b44/

• (00:00) - Introduction and Background
• (03:06) - Feasibility Assessment
• (06:07) - Importance of Understanding the Local Standard of Care
• (10:40) - Impact of Standard of Care on Patient Enrollment
• (25:28) - Challenges of Assessing the Standard of Care
• (27:09) - Standard of Care in Selecting Comparators and Budget Implications

Meet Annabel de Maria Bosch - the Chief Patient Officer at Alira Health with nearly three decades of experience in patient engagement across the pharmaceutical industry. In this insightful conversation, Annabel shares her unique perspective on the critical importance of understanding the patient journey and its impact on clinical trial success.

Follow Maya Zlatanova: https://www.linkedin.com/in/mayazlatanova/
Follow Annabel de Maria Bosch: https://www.linkedin.com/in/annabeldemaria/

Annabel shares some very curious studies in the episode:

1)Stergiopoulos et al., Measuring the Impact of Patient Engagement and Patient Centricity in Clinical Research and Development (2020);

2)Levitan et al., Assessing the Financial Value of Patient Engagement: A Quantitative Approach from CTTI’s Patient Groups and Clinical Trials Project (2018);

3)Getz, Establishing Return-on-Investment Expectations for Patient-Centric Initiatives (2015)

Meet Joy Milne, a remarkable woman whose unique sense of smell is revolutionizing the world of Parkinson's research. In this episode, Joy shares her personal story of love, loss, and unwavering determination to make a difference in the lives of those affected by Parkinson's, from her groundbreaking work with researchers at the University of Manchester to her advocacy for greater awareness of the challenges faced by women with the disease.

Follow Maya Zlatanova: https://www.linkedin.com/in/mayazlatanova/

Learn more about Joy Milne and her work:

• https://www.nytimes.com/2024/06/14/magazine/parkinsons-smell-disease-detection.html
• https://www.npr.org/sections/health-shots/2020/03/23/820274501/her-incredible-sense-of-smell-is-helping-scientists-find-new-ways-to-diagnose-di

• (00:00) - Introduction to Joy Milne and her Advocacy Work
• (05:40) - Balancing Biotech Work and Caregiving
• (06:34) - Challenges in Parkinson's Research and Lack of New Medications
• (10:37) - Differences in Parkinson's Disease between Men and Women
• (14:18) - Encouraging Early Diagnosis in Parkinson's
• (16:56) - Variations in Parkinson's Care across Countries
• (18:43) - The Importance of Patient Engagement in Clinical Trials
• (21:04) - Challenges in Communication between Researchers and Patient Advocates
• (23:34) - The Benefits of a Person-Based Approach in Healthcare
• (25:49) - The Implications of Patient Public Involvement in Research
• (29:20) - Positive Changes and Future Outlook in Parkinson's Research