This Week in Virology

By: Vincent Racaniello
  • Summary

  • TWiV is a podcast about viruses - the kind that make you sick.
    Vincent Racaniello 2022
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Episodes
  • TWiV 1198: Clinical update with Dr. Daniel Griffin
    Mar 8 2025
    In his weekly clinical update, Dr. Griffin with Vincent Racaniello deliberate the effect of the absence of US foreign aid on the Ebola outbreak in Uganda and death of two children, continued use of nOPV2 in Gaza and the utter failure of type 2 poliovirus removal from the oral poliovirus vaccine, growing measles outbreak in the US including the death of a second child, measles infection parties, the use of fat soluble vitamin A and fish liver oil as anti-viral therapies as well as the history and proven safety of the measles vaccine before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what happens when antiviral therapy is delayed, provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions, long COVID interventions. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode African region: outbreaks and other emergencies(WHO Bitstream)US withdrawal……death of 4 year old children from Ebola (CIDRAP)Science and health writer Apoorva Mandavilli (NY Times)US foreign aid pullback……death of 4 year old in Uganda (NY Times) Another Ebola death reported in Kampala (Monitor)African region: outbreaks and other emergencies(WHO Bitstream)More than 600,000 doses of nOPV2 in Gaza last week (GPEI)Utter failure of the global withdrawal of the Sabin oral poliovirus type 2 vaccine 2016 (Science)Measles 159 in Texas…. (Texas Health and Human Services) Second child dies in the growing measles outbreak (Washington Post)2025 Measles outbreak guidance (New Mexico Health)Lea county resident tests positive for measles after death (New Mexico Health)Robert F Kennedy Jr article series (The Guardian)Kennedy Jr backtracks and says US measles outbreak is now a ‘top priority’ for health department (The Guardian)RFK Jr. Says Ending Measles Outbreak Is Priority (Wall Street Journal)RFK Jr. Sparks Anti-Vaxxer Anger: ‘No Different Than Fauci’ (Newsweek)Amid West Texas measles outbreak, vaccine resistance hardens (Washington Post)How to protect your children during a measles outbreak (healthychildren.org)Measles vaccination protects against virus infection and other infections (Science)MEASLES (WHO)C.D.C. Sends ‘Disease Detectives’ to Texas for Measles Outbreak(NY Times) Studies on an attenuated measles-virus vaccine — clinical, virologic and immunologic fffects of vaccine in institutionalized children(NEJM)Studies on an attenuated measles-virus vaccine — clinical and antigenic effects of vaccine in institutionalized children (NEJM)Studies on an attenuated measles-virus vaccine — administration of vaccine by several routes (NEJM)Studies on an attenuated measles-virus vaccine — clinical, antigenic and prophylactic effects of vaccine in institutionalized and home-dwelling children(NEJM)Studies on an attenuated measles-virus vaccine — clinical, antigenic and prophylactic effects of vaccine in institutionalized children(NEJM)Studies on an attenuated measles-virus vaccine — clinical, antigenic and prophylactic effects of vaccine in home-dwelling children (NEJM)Studies on an attenuated measles-virus vaccine — general summary and evaluation of the results of vaccination(NEJM)Cooperative measles vaccine field trial (Pediatrics)A collaborative study of measles vaccines in five united states communities (American Journal of Public Health)A field trial of inactivated measles virus vaccine in young school children(JAMA Network)Prevention of natural and experimental measles with the vaccine(JAMA Network)A field trial in young school children(JAMA Network)Measles vaccination before the measles-mumps-rubella vaccine (American Journal of Public Health)The status of measles vaccines (Journal of the National Medical Association)Measles, mumps, and rubella (mmr) vaccination: what everyone should know (CDC Vaccines & Immunizations)Clinical review memo- measles, mumps, rubella (FDA) History of the measles vaccine (WHO) Vitamin A and the measles (Yahoo! News)As measles spreads, Kennedy embraces remedies like cod liver oil (NY Times)Parents are holding ‘measles parties’ in the U.S., alarming healthexperts(Global News)Influenza: Waste water scan for 11 pathogens (WastewaterSCan)US respiratory virus activity (CDC Respiratory Illnesses)Weekly surveillance report: cliff notes (CDC FluView)RSV: Waste water scan for 11 pathogens (WastewaterSCan) Weekly US influenza surveillance report (CDC FluView)US respiratory virus activity (CDC Respiratory Illnesses)RSV-Network (CDC Respiratory Syncytial virus Infection)Waste water scan for 11 pathogens (WastewaterSCan)COVID-19 deaths (CDC)COVID-19 national and regional trends (CDC)COVID-19 variant tracker (CDC)SARS-CoV-2 genomes galore (Nextstrain)...
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    43 mins
  • TWiV 1197: The long and short of influenza
    Mar 2 2025
    TWiV reviews passing of Ann Palmenberg, deadly illness in western Congo, US disruption of mpox and ebolavirus programs, first measles death in Texas outbreak, flu vaccine selection meeting postponed, US withdraws from polio, malaria, HIV programs and more, clade 2.3.4.4b H5N1 viruses have a long HA stalk, and systems vaccinology to identify predictors of durable antibody response to multiple vaccines in humans. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTVASV 2025 Ann Palmenberg dies (Cress)Ann at Chumakov Symposium (YouTube) Unknown illness in Congo (NY Times)Bad news about mpox outbreak (NPR)US interrupts Ebola prevention program (NPR)First measles death in Texas (Texas Trib) Flu vaccine selection meeting canceled (NY Times)US ends funding for polio, HIV, malaria and more (NY Times)Clade 2.3.4.4b H5N1 neuraminidase has a long stalk (mBio)Predictors of durable antibody responses to vaccines (Nat Immunol)Review of adjuvants (Vaccinol Methods Vacc Res)Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Video of the Northern Lights from Space Rich – Vaccination for Sudan Ebola virus disease Alan – Specialized moth wing scales give it 3-D camouflage (news and paper) Vincent – WHO Recommendations for Influenza Vaccine Composition for the 2025-2026 Northern Hemisphere Influenza Season Listener Picks Gerry – Eukaryotic Transcription Anne – The science of the solar system Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
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    1 hr and 41 mins
  • TWiV 1196: Clinical update with Dr. Daniel Griffin
    Mar 1 2025
    In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the downfall of public health from “postponement” of the advisory committee on immunization practices and the FDA VRBPAC influenza strain selection meetings to how the communication pause prevents public notice of NIH study section meetings, and withdrawal of CDC promotions for the ‘flu vaccine’ before discussing the end of Ebola outbreak in Uganda, funding from Saudi Arabia for polio eradication, the continuing and growing measles outbreak in the US including misinformation from the Secretary of HHS, highly pathogenic avian flu and its economic effect, ie the cost of eggs before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and FDA approval of adjuvanted Novovax COVID vaccine. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Phantom ACIP (CDC) Postponement of ACIP…..hummmm (STATNews)Influenza Strain selection VRBPAC cancelled (Reuters)How NIH funded research is impacted by government communication pause (NY Times)Can be reviewed but still no money (STATNews)Final push to end Ebola in Uganda (WHO Uganda)Saudi Arabia sponsors polio eradication effort (GPEI)) $500 million from Saudi Arabia to immunize 370 million children against polio (CIDRAP)Measles 124 in Texas…. (Texas Health and Human Services)A Texas child who was not vaccinated has died of measles(AP News)The Measles book-(Apple Books)Measles vaccination protects against virus infection and other infections (Science)Measles deadliest sequelae (MEDPAGE TODAY)Measles cases and outbreaks (CDC Measles)Unvaccinated Child Dies of Measles in Texas Outbreak(NY Times)Texas child is first reported US measles death in a decade as outbreak hits more than 130 (Reuters)Trump’s cabinet meeting: Kennedy Shocker “Not unusual”……..seriously! (YouTube) First measles death reported in Texas as Kennedy downplays the outbreak (NBC News)Measles cliff notes: symptoms timeline (Substackdn)Annual state immunization report (Texas Health and Human Services)Measles imported into Kentucky…….no tariffs? (Commonwealth of Kentucky)Egg shortage affect flu shots? (MEDPAGE TODAY) Which Came First, the Chicken Slaughter or the Egg Shortage(Wall Street Journal) Avian Influenza in Birds: Causes and How It Spreads (CDC Avian Influenza)Agriculture Secretary Brooke Rollins: My Plan to Lower Egg Prices (Wall Street Journal)Influenza: Waste water scan for 11 pathogens (WastewaterSCan)US respiratory virus activity (CDC Respiratory Illnesses)Weekly surveillance report: clift notes (CDC FluView)RSV: Waste water scan for 11 pathogens (WastewaterSCan) Weekly US influenza surveillance report (CDC FluView)US respiratory virus activity (CDC Respiratory Illnesses)Trump administration yanks CDC flu vaccine campaign(NPR)RSV-Network (CDC Respiratory Syncytial virus Infection)New wild to mild campaign drives key message to tame flu and reset expectations(CDC Influenza)Waste water scan for 11 pathogens (WastewaterSCan)COVID-19 deaths (CDC)COVID-19 national and regional trends (CDC)COVID-19 variant tracker (CDC)SARS-CoV-2 genomes galore (Nextstrain)Effectiveness of the original monovalent messenger RNA Coronavirus Disease 2019 (COVID-19) vaccination series against hospitalization for COVID-19–Associated venous thromboembolism (JID)Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC)NIH COVID-19 treatment guidelines (NIH)Drug interaction checker (University of Liverpool)Demographic variation in US outpatient hydroxychloroquine and ivermectin use during the COVID-19 pandemic (HealthAffairs)Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society)Alleviation of COVID-19 symptoms and reduction in healthcare utilization among high-risk patients treated With nirmatrelvir/ritonavir (NMV/R) (CID)Molnupiravir safety and efficacy (JMV)Convalescent plasma recommendation for immunocompromised (ID Society)What to do when sick with a respiratory virus (CDC)When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)Managing healthcare staffing shortages (CDC)Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org)Daniel Griffin’s evidence based medical practices for long COVID (OFID)Long COVID hotline (Columbia : Columbia University Irving Medical Center)The answers: Long COVID Interventions for Long COVID: A Narrative Review (Journal of General Internal Medicine)...
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    59 mins

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