• State of the Art Monitoring and Diagnostics in Chronic Myeloid Leukemia: the Philadelphia Chromosome and Future of CML

  • Sep 28 2023
  • Length: 21 mins
  • Podcast

State of the Art Monitoring and Diagnostics in Chronic Myeloid Leukemia: the Philadelphia Chromosome and Future of CML cover art

State of the Art Monitoring and Diagnostics in Chronic Myeloid Leukemia: the Philadelphia Chromosome and Future of CML

  • Summary

  • Drs Michael J. Mauro and Jerald P. Radich discuss monitoring and diagnostics in chronic myeloid leukemia, including the Philadelphia chromosome and how it plays into the current treatment of CML.

    Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/989028). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

    Resources

    Chronic Myelogenous Leukemia (CML) https://emedicine.medscape.com/article/199425-overview

    Genetics, Philadelphia Chromosome https://www.ncbi.nlm.nih.gov/books/NBK560689/

    Reverse Transcriptase-Polymerase Chain Reaction https://emedicine.medscape.com/article/2093395-overview

    Why Is It Critical to Achieve a Deep Molecular Response in Chronic Myeloid Leukemia? https://pubmed.ncbi.nlm.nih.gov/33054104/

    Precision Oncology: Who, How, What, When, and When Not? https://ascopubs.org/doi/full/10.1200/EDBK_174176

    Discovery of the Philadelphia Chromosome: A Personal Perspective https://pubmed.ncbi.nlm.nih.gov/17671636/

    Dr. Janet Davison Rowley https://cfmedicine.nlm.nih.gov/physicians/biography_282.html

    Metaphase https://www.genome.gov/genetics-glossary/Metaphase

    A Primer on Genetic Testing https://www.medscape.com/viewarticle/505220_7

    WHO 2016 Definition of Chronic Myeloid Leukemia and Tyrosine Kinase Inhibitors https://pubmed.ncbi.nlm.nih.gov/31612694/

    Flow Cytometry: An Overview https://pubmed.ncbi.nlm.nih.gov/29512141/

    Accelerated Phase Chronic Myelogenous Leukemia https://www.cancer.gov/publications/dictionaries/cancer-terms/def/accelerated-phase-chronic-myelogenous-leukemia

    Treatment-Free Remission in CML: Who, How, and Why? https://pubmed.ncbi.nlm.nih.gov/29222243/

    Digital PCR for BCR-ABL1 Quantification in CML: Current Applications in Clinical Practice https://pubmed.ncbi.nlm.nih.gov/33283168/

    Tyrosine Kinase Inhibitors https://www.ncbi.nlm.nih.gov/books/NBK563322/

    t(14;18) Translocations and Risk of Follicular Lymphoma https://pubmed.ncbi.nlm.nih.gov/18648003/

    CHIP https://www.cancer.gov/publications/dictionaries/genetics-dictionary/def/chip

    The Max Foundation https://themaxfoundation.org/

    BCR-ABL Fusion Gene https://www.cancer.gov/publications/dictionaries/cancer-terms/def/bcr-abl-fusion-gene

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