Preterm birth is the greatest cause of neonatal mortality and morbidity, with infants born extremely preterm at highest risk. Author Brett J. Manley, PhD, the Royal Women’s Hospital, Melbourne, Australia, discusses a new study of the effect of intratracheal corticosteroid administration on survival free of bronchopulmonary dysplasia in preterm infants, with JAMA Deputy Editor Tracy A. Lieu, MD, MPH.

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Preventing obesity in early childhood is challenging for clinicians and families. Authors Eliana M. Perrin, MD, MPH, of Johns Hopkins University, and William J. Heerman, MD, MPH, of Vanderbilt University, join JAMA Deputy Editor Tracy Lieu, MD, to discuss "A Digital Health Behavior Intervention to Prevent Childhood Obesity: The Greenlight Plus Randomized Clinical Trial."

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• A Digital Health Behavior Intervention to Prevent Childhood Obesity

A new study published in JAMA found that drug-related supply chain issue reports were 40% less likely to result in meaningful drug shortages in Canada compared with the US. Authors Kate Suda, PharmD, MS, of University of Pittsburgh School of Medicine, and Mina Tadrous, PharmD, PhD, of University of Toronto, discuss this and more with JAMA Deputy Editor Joseph S. Ross, MD, MHS.

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• Differences in Drug Shortages in the US and Canada
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In the US, childbirth typically occurs in hospitals or accredited birth centers. President of the American College of Obstetricians and Gynecologists Stella Marie Dantas, MD, speaks with JAMA Deputy Editor Linda Brubaker, MD, MS, about newly proposed advanced birth centers that would permit higher-risk births, with concerns for patient safety and rural obstetric care access.

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• Advanced Birth Centers and the Effect on Maternity Care

The Declaration of Helsinki originated in 1964, developed by the World Medical Association (WMA). Process Chair Jack S. Resneck Jr, MD, discusses the 2024 updates to the Declaration of Helsinki with JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.

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Transfusion strategy for patients with acute brain injury, telehealth care, acute kidney injury after cardiac surgery, and weaning ventilatory support are the topics of 4 trials published in JAMA and presented at the 2024 European Society of Intensive Care Medicine meeting. JAMA Associate Editor Christopher Seymour, MD, MSc, joins Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss.

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• Shifting Balance of the Risk-Benefit of Restrictive Transfusion Strategies in Neurocritically Ill Patients—Is Less Still More?
• Evaluating Complex Technological Innovations in Critical Care—Current Challenges and Future Directions
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Gastric cancer is a leading cause of cancer death globally. Chronic H pylori infection is the primary cause of gastric cancer, responsible for at least 80% of the new cases. Constanza Camargo, PhD, of the National Cancer Institute joins JAMA Associate Editor John M. Inadomi, MD, to discuss co-testing with FIT and H pylori stool antigen to help prevent gastric cancer.

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• Fecal Immunochemical Test and Helicobacter pylori Stool Antigen Co-Testing
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Fever is associated with worse outcomes in patients with stroke, but whether preventing fever improves outcomes is unclear. David M. Greer, MD, MA, speaks with JAMA Associate Editor Jeffrey L. Saver, MD, about fever prevention in patients with acute stroke and its impact on functional outcomes.

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• Fever Prevention in Patients With Acute Vascular Brain Injury
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