• FGA-FGB-FGG - The Clot Thickens

  • Nov 23 2024
  • Length: 7 mins
  • Podcast

FGA-FGB-FGG - The Clot Thickens

Listen for free

View show details

  • Summary

  • The FGA, FGB, and FGG genes encode the three polypeptide chains—alpha, beta, and gamma—that assemble to form fibrinogen. Fibrinogen is a critical plasma protein involved in blood clotting, wound healing, and maintaining hemostasis. It serves as a precursor to fibrin, forming a mesh-like structure that stabilizes blood clots. Beyond clot formation, fibrinogen plays roles in inflammation, tissue repair, and cellular signaling, making it essential for vascular health and recovery from injury.

    Mutations or dysregulation in these genes can lead to disorders such as dysfibrinogenemia or hypofibrinogenemia, impacting clot formation and wound healing. These genes are also pivotal in therapeutic strategies targeting coagulation disorders and cardiovascular diseases.
    Show More Show Less
Show More Show Less

What listeners say about FGA-FGB-FGG - The Clot Thickens

Average Customer Ratings

Reviews - Please select the tabs below to change the source of reviews.

Audible.com.au reviews

Amazon Reviews
No Reviews are Available
In the spirit of reconciliation, Audible acknowledges the Traditional Custodians of country throughout Australia and their connections to land, sea and community. We pay our respect to their elders past and present and extend that respect to all Aboriginal and Torres Strait Islander peoples today.