• Episode 57: Fen-Phen

  • Sep 18 2024
  • Length: 1 hr and 12 mins
  • Podcast

Episode 57: Fen-Phen

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  • Summary

  • In the 1990s, a new diet drug combination swept the US, promising an easy way to drop weight quickly. Soon thereafter, Redux joined the ranks, but the fatal side effects would soon come to light when thousands were injured with heart disease and neurotoxicity. --- Follow us on social media: Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/lethaldosepod/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@lethaldosepod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCQd4E_g4mt9G-rg7vT8nwvw⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Tumblr: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tumblr.com/lethaldosepod⁠⁠⁠⁠⁠⁠ --- Cohen, E., & McDermott, A. (1998). Who's fat? New definition adopted. CNN. Retrieved 29 Jul 2024, from http://www.cnn.com/HEALTH/9806/17/weight.guidelines/ Cohen, K. (2003). Fen Phen Nation. Frontline. Retrieved 24 Jul 2024, from https://www.pbs.org/wgbh/pages/frontline/shows/prescription/hazard/fenphen.html Fauber, J., & Fiore, K. (2015). Slippery Slope: Fen-Phen Users Recall a 'Miracle' Turned Nightmare. MedPage Today. Retrieved 05 Aug 2024, from https://www.medpagetoday.com/special-reports/slipperyslope/51044 Fishman, A. P. (1999). Aminorex to Fen/Phen: An epidemic foretold. Circulation, 99, 156-161. Fox, M. (2012). FDA approves weight loss drug, with a new name - Qsymia. NBC News. Retrieved 15 Aug 2024, from https://www.nbcnews.com/health/health-news/fda-approves-weight-loss-drug-new-name-qsymia-flna891310 Halsey, E. (1997). Woman says infant son is fen-phen victim. CNN. Retrieved 05 Aug 1997, from http://www.cnn.com/HEALTH/9710/10/fen.phen.babies/ Himes, J. H., & Bouchard, C. (1985). Do the new Metropolitan Life Insurance weight-height tables correctly assess body frame and body fat relationships? AJPH, 75(9), 1076-1079. Hutcheson, J. D., Setola, V., Roth, B. L., & Merryman, W. D. (2011). Serotonin receptors and heart valve disease - It was meant 2B. Pharm & Thera, 132(2), 146-157. Johnson, D. B., & Quick, J. (2023). Topiramate and Phentermine. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK482165/ Kolata, G. (1997). How Fen-Phen, A Diet 'Miracle,' Rose and Fell. The New York Times. Retrieved 06 Aug 2024, from https://www.nytimes.com/1997/09/23/science/how-fen-phen-a-diet-miracle-rose-and-fell.html Madrigal, A. (2008). New Weight-Loss Drug Like Fen-Phen, But Not As Heart Breaking. Wired. Retrieved 29 Jul 2024, from https://www.wired.com/2008/01/weight-loss-dru/ Mundy, A. (2001). Dispensing With the Truth. St. Martin's Press. Phentermine. (2020). In LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.ncbi.nlm.nih.gov/books/NBK547916/ The Problem with Fen-Phen. (1998). Retrieved 24 Jul 2024, from https://www.sciencedaily.com/releases/1998/09/980902053528.htm Samanta, D. (2022). Fenfluramine: A review of pharmacology, clinical efficacy, and safety in epilepsy. Children (Basel), 9(8), 1159. Saul, S. (2005). Fen-Phen Case Lawyers Say They'll Reject Wyeth Offer. The New York Times. Retrieved 14 Aug 2024, from https://www.nytimes.com/2005/02/17/business/fenphen-case-lawyers-say-theyll-reject-wyeth-offer.html Van Norman, G. A. (2023). Off-label use vs. Off-label marketing of drugs. JACC Basic Tansl Sci, 8(2), 224-233.
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