In this electrifying episode of The Uterine Sound podcast, hosts Carla Pecoraro, Mel Acreman, and Anne Woolfield dive into groundbreaking gynaecology oncology research that could transform patient care.

First, we unravel the mysteries of the PLCO study—“Effect of Screening on Ovarian Cancer Mortality.” This 2011 JAMA blockbuster pits CA125 and transvaginal ultrasound against routine care in a high-stakes battle for ovarian cancer mortality. With over 78,000 women in the mix, the results are eye-opening: while screening increased cancer diagnoses, it didn’t cut mortality rates. Plus, the fallout from false positives led to serious complications. Tune in to find out why this study could reshape how we think about ovarian cancer screening.

Next, the podcast heats up with the LACE trial—“Effect of Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy on Disease-Free Survival.” Published in 2017, this study compares laparoscopic hysterectomy to the traditional abdominal approach in treating stage 1 endometrial cancer. Discover how TLH stacks up against TAH in terms of disease-free survival and why TLH's benefits might make it the new gold standard for quicker recoveries and less post-op pain.

Get ready for a dynamic episode packed with crucial insights from these landmark trials. Whether you're a clinician or just curious, this episode delivers cutting-edge information that’s essential for understanding and improving gynaecological cancer care. Don’t miss out—this is a must-listen for anyone invested in women's health!