• Episode 4: Dan Kaufman on off-the-shelf cell therapy and Manhattans

  • Mar 31 2024
  • Length: 44 mins
  • Podcast

Episode 4: Dan Kaufman on off-the-shelf cell therapy and Manhattans

  • Summary

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    UCSD's Dan Kaufman, an innovator in the field of induced pluripotent cell (iPSC)-derived natural killer cell therapies, talks to Andy and JC about the latest in allogeneic and autologous immune and regenerative cell therapies at the 2024 Keystone symposium on Emerging Cell Therapies.

    02:55 Sourcing and expanding NK cells
    05:59 Off-the-shelf versus self
    09:26. Clinical trials and manufacturing
    13:40. Stealth, immune cloaking and protein manufacture
    16:51. Safety, cost, availability and standardization
    22:00. Stampede into autoimmune disease
    28:59. Neurological cell therapies and beyond
    33:30. Off the shelf and in vivo engineering
    38:13. Commercialization headaches
    39:51. Dan’s drink


    The Manhattan:
    2 Oz rye whiskey,
    1 Oz sweet vermouth,
    2 dashes aromatic bitters.

    DIRECTIONS: Stir on ice for 45 sec and strain over a coupe glass. Garnish with a maraschino cherry.


    The Mixer music “Pour Me Another” courtesy of Smooth Moves!

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