For episode 79 of Entrepreneur Rx, John interviews rockstar Esther Dyson, founder of Wellville, a 10-year nonprofit project dedicated to demonstrating the value of long-term investment in health and equity. Esther has been or is a director of many companies such as 23andMe, Avanlee Care, Meetup, and WPP Group. In addition, Esther is an active angel investor and also enjoys sitting on the boards of several nonprofits, such as Charity Navigator, ExpandED Schools, Long Now and The Commons Project. 

This interview starts off with her explaining the Wellville project and her impressive background (she has even trained as a backup cosmonaut). Esther emphasizes the importance of asking questions and learning from others, rather than trying to have all the answers. Esther then shares her experiences as an angel investor, highlighting the qualities she looks for in founders, such as creativity, resilience, vision and humility. 

Esther goes on to express concern about society's addiction to instant gratification of all kinds – drugs, food, VC exits and the like. She stresses the importance of providing support and resources for maternal care, doula services, and parenting education to create a stable foundation for future generations and to “train” babies to be healthy humans resistant to manipulation…by trained AIs. Esther encourages individuals to face their fears and take risks, emphasizing the value of having a support system in place. She then concludes by reminding listeners that failure is a natural part of life and should be embraced as a learning opportunity.