• Diagnosis and Management of Lipid Transfer Protein Allergy—A BSACI Clinical Practice Statement

  • Apr 7 2025
  • Length: 9 mins
  • Podcast

Diagnosis and Management of Lipid Transfer Protein Allergy—A BSACI Clinical Practice Statement

  • Summary

  • Keywords

    Allergy, lipid transfer protein, food allergy, pollen food syndrome, diagnosis, management, diet, adrenaline, co-factors, clinical research

    Summary

    In this episode of the Clinical and Experimental Allergy podcast, hosts Mo Shamji and Robert Boyle engage with Dr. Isabel Skypala, a consultant allergy dietician, to discuss the increasing recognition of lipid transfer protein (LTP) allergy in the UK. Dr. Skypala shares insights into the challenges of diagnosing LTP allergy, particularly due to its overlap with pollen food syndrome, and emphasizes the importance of a thorough clinical history. The conversation also covers management strategies for patients with LTP allergy, including the role of co-factors, the creation of safe diets, and considerations for the use of adrenaline auto-injectors. Dr. Skypala highlights the need for individualized approaches in allergy management, ensuring that patients can maintain a balanced diet while avoiding triggers.

    Takeaways

    • LTP allergy is increasingly recognized in the UK.
    • Diagnosis requires careful clinical history taking.
    • Symptoms of LTP allergy can vary significantly.
    • Cofactors like exercise and alcohol can trigger reactions.
    • Individualized dietary plans are essential for patients.
    • Food challenges can help identify safe foods.
    • Different varieties of fruits may be tolerated differently.
    • Adrenaline auto-injectors may be necessary for high-risk patients.
    • Management strategies must consider lifestyle factors.
    • Collaboration among clinicians is vital for effective allergy management.

    Chapters

    00:00 Introduction to the speakers

    01:17 Understanding Lipid Transfer Protein Allergy

    02:54 Challenges in Diagnosing LTP Allergy

    04:22 Management Strategies for LTP Allergy with co-factors

    05:32 Dietary Considerations and Food Challenges

    07:21 Adrenaline Auto-Injectors and Risk Assessment

    08:41 Closing the podcast

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