#196

New College-Style Sweatshirt!

Melissa and Jam delve into the science behind ibuprofen, exploring why it takes around 30 minutes to work. The discussion covers the chemistry of ibuprofen, including the concept of chiral molecules and enantiomers—molecules with mirror-image forms—highlighting how only one form of ibuprofen works effectively. The episode explains why both forms are included in the medication due to production challenges and discusses recent findings about ibuprofen's potential in cancer treatment. Additionally, the show features various fun facts about ibuprofen, aspirin comparisons, environmentally friendly production methods, and more.

00:00 Introduction and Episode Overview
05:07 Chemistry Lesson: Handedness of Molecules
17:52 Ibuprofen's Chiral Nature and Its Effects
19:15 The Racemic Mixture of Ibuprofen
24:06 The Wastefulness of Chemistry
24:29 Challenges of Purifying Enantiomers
25:16 Economic and Environmental Considerations
26:28 Understanding Ibuprofen's Handedness
27:26 The Debate on Enantiomer Separation
34:45 Fun Facts About Ibuprofen
39:55 Green Chemistry and Ibuprofen
45:42 Community and Closing Remarks

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276492/
2. https://thispodcastwillkillyou.com/wp-content/uploads/2021/07/TPWKY-Episode-29-Aspirin.pdf
3. https://www.chemistryworld.com/podcasts/ibuprofen/4011375.article
4. https://pubs.acs.org/doi/epdf/10.1021/bi010045s?ref=article_openPDF
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/ 6. Garret & Grisham Biochemistry Textbook

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

Thanks to our monthly supporters

• Scott B
• Jessie Reder
• Ciara Linville
• J0HNTR0Y
• Jeannette Napoleon
• Cullyn R
• Erica Bee
• Elizabeth P
• Sarah Moar
• Rachel Reina
• Letila
• Katrina Barnum-Huckins
• Suzanne Phillips
• Venus Rebholz
• Lyn Stubblefield
• Jacob Taber
• Brian Kimball
• Emerson Woodhall
• Kristina Gotfredsen
• Timothy Parker
• Steven Boyles
• Chris Skupien
• Chelsea B
• Bri McAllister
• Avishai Barnoy
• Hunter Reardon

Check out our website at chemforyourlife.com

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Question and Response #60

New College-Style Sweatshirt!

In this episode of 'Ask a Chemist' on the Chemistry for Your Life podcast, hosts Melissa and Jam tackle a diverse range of fun and fascinating chemistry questions. Topics include the differences between oxygen in water and air, the properties of jello, the mystery behind glitter, and the impact of pasteurization on milk safety. The episode also addresses more complex inquiries such as infrared spectroscopy and the oxidative stability of whole grain flour.

00:00 Introduction to Ask a Chemist
02:39 The Pasteurization Question
08:51 What Makes Jello Jello?
10:06 Oxygen in Water vs. Air
12:40 The Mystery of Glitter
15:46 Infrared Spectroscopy and Northern Lights
18:29 Oxidation in Flour
22:17 Collagen and Muscle Building
26:06 Listener Reviews and Closing Remarks

1. https://www.maastrichtuniversity.nl/l.vanloon

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

Thanks to our monthly supporters

• Autoclave
• Chelsea M
• Dorien V
• Scott B
• Jessie Reder
• Ciara Linville
• J0HNTR0Y
• Jeannette Napoleon
• Cullyn R
• Erica Bee
• Elizabeth P
• Sarah Moar
• Rachel Reina
• Letila
• Katrina Barnum-Huckins
• Suzanne Phillips
• Venus Rebholz
• Lyn Stubblefield
• Jacob Taber
• Brian Kimball
• Emerson Woodhall
• Kristina Gotfredsen
• Timothy Parker
• Steven Boyles
• Chris Skupien
• Chelsea B
• Bri McAllister
• Avishai Barnoy
• Hunter Reardon

Check out our website at chemforyourlife.com

Watch our episodes on YouTube

Find us on Instagram, Twitter, and Facebook @ChemForYourLife

#195

New College-Style Sweatshirt!

In this episode of Chemistry For Your Life, hosts Melissa and Jam delve into the science behind ibuprofen, a common pain reliever. They discuss the role of prostaglandins in inflammation, how ibuprofen inhibits the cox enzyme to reduce pain, and the body's natural immune response. They also share personal anecdotes about meeting listeners, their favorite types of ibuprofen, and explore plans for future episodes about other pain relievers.

00:00 Introduction and Personal Anecdote
01:00 Meet the Hosts
01:11 Exciting Announcements
02:46 Listener Shoutout
05:41 Understanding Pain and Inflammation
06:48 The Role of Prostaglandins
14:38 How Ibuprofen Works
18:15 Personal Experiences with Pain
21:16 Preview of Next Episode
22:10 Understanding Pain and Inflammation
23:07 The Role of Prostaglandins
24:50 Enzymes and Their Functions
27:11 How Ibuprofen Works
35:11 Personal Experiences with Ibuprofen
40:42 Supporting the Show and Final Thoughts

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276492/
2. https://thispodcastwillkillyou.com/wp-content/uploads/2021/07/TPWKY-Episode-29-Aspirin.pdf
3. https://www.chemistryworld.com/podcasts/ibuprofen/4011375.article
4. https://pubs.acs.org/doi/epdf/10.1021/bi010045s?ref=article_openPDF
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/ 6. Garret & Grisham Biochemistry Textbook

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

Thanks to our monthly supporters

• Scott B
• Jessie Reder
• Ciara Linville
• J0HNTR0Y
• Jeannette Napoleon
• Cullyn R
• Erica Bee
• Elizabeth P
• Sarah Moar
• Rachel Reina
• Letila
• Katrina Barnum-Huckins
• Suzanne Phillips
• Venus Rebholz
• Lyn Stubblefield
• Jacob Taber
• Brian Kimball
• Emerson Woodhall
• Kristina Gotfredsen
• Timothy Parker
• Steven Boyles
• Chris Skupien
• Chelsea B
• Bri McAllister
• Avishai Barnoy
• Hunter Reardon

Check out our website at chemforyourlife.com

Watch our episodes on YouTube

Find us on Instagram, Twitter, and Facebook @ChemForYourLife