In this episode, drug discovery scientist Artem Evdokimov discusses the science of pharmaceutical development, from historical breakthroughs to the current landscape. He shares insights on antibiotics resistance, the obesity drug Ozempic, and technical details of drug screening methods like DNA-encoded libraries.

The conversation covers the economics of drug development, the potential of AI, and broader philosophical questions about human health and medicine. Evdokimov emphasizes the importance of avoiding oversimplification in science while highlighting both the triumphs and ongoing challenges in pharmaceutical research.

03:18 Historical Roots of Medicine
05:33 Evolution of Drug Delivery Methods
12:52 Modern Drug Discovery and Challenges
45:39 Understanding the Drug Discovery Process
47:30 Challenges in Gene Therapy
49:26 Complexities of Human Physiology
53:14 The Role of Receptors and Hormones
01:28:12 The Selenium Shortage and Shampoo Dilemma
01:28:54 Challenges in Drug Manufacturing and Distribution
01:34:23 Antibiotic Resistance: A Growing Concern
01:45:18 The Future of Drug Discovery and AI
02:11:01 Exploring AI and Drug Discovery
02:11:41 Outsourcing in Pharma: Pros and Cons
02:13:56 High Throughput Screening and Machine Learning
02:16:37 Challenges and Future of Drug Discovery

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In this episode of the 632nm podcast, Nader Engheta shares his journey and experiences within the field of electromagnetics, from his early days at the University of Tehran and Caltech, to his current research in optical metatronics and nonlinear dynamics.

He discusses the importance of motivation and curiosity in scientific research, the potential of optics in AI, and the exciting new possibilities for combining knowledge from different fields. Engheta also touches on his experiences in industry, interdisciplinary teaching, and offers advice to young researchers.

02:19 Fascination with Electromagnetics
03:14 Journey from Tehran to Caltech
05:39 Exploring Chirality and Metamaterials
08:21 Innovations in Polarization Imaging
36:12 Exploring Antennas and Metatronics
36:46 Dream Job in the Tech Industry
37:24 Optics and Artificial Intelligence
39:44 Brain Waves and Neuroscience
53:20 Optical Computing vs. Electronics
01:15:55 Exploring Optical and Electronic Constraints
01:17:47 Optical Computing: Efficiency and Challenges
01:20:58 Historical Insights and Modern Applications
01:26:20 Nonlinearity in Optical Systems
01:32:59 Future Directions and Advice for Young Researchers

In this episode of the 632-nanometer podcast, we explore the evolution of quantum computing with theoretical physicists and experimentalists Peter Zoller and Ignacio Cirac, two pioneers in the field. They recount their personal journeys and discuss key breakthroughs in the development of trapped ion quantum computing.

What are the fundamental challenges of quantum computing, and how did researchers overcome them? What detection methods were initially considered, and how has the approach evolved? In this podcast, you'll find the answers to these questions and learn about significant milestones, including the early experiments by Dave Wineland and Chris Monroe, as well as the role of fault-tolerant quantum computing and error correction in shaping the future of this technology.

We also discuss the commercialization of quantum computing, its potential applications, and the future opportunities it presents for young scientists. Zoller and Cirac address foundational questions about quantum physics, the broader implications of their work for science and technology, and share strategic advice for aspiring researchers entering the field.

01:33 The Meeting of Minds: How We Met
02:19 Early Collaborations and Research
03:35 The Birth of Trapped Ion Quantum Computing
05:51 Challenges and Innovations in Quantum Computing
08:47 The Role of Atomic Clocks and Other Systems
15:20 Overcoming Skepticism and Technical Hurdles
21:28 Advancements and Future Directions
36:38 Exploring Magnetic Field Gradients in Quantum Computing
37:00 NMR vs. Ion Trap Quantum Computing
37:40 Reflecting on Influential Papers and Collaborations
38:48 Quantum Simulators and Optical Lattices
40:50 Quantum Communication and Entanglement
47:42 Solid State vs. AMO Systems
53:49 The Future of Quantum Computing
01:02:54 Philosophical and Speculative Questions in Quantum Physics